Lymphedema patients often complain about pain in the affected extremity. Theoretically, chronic lymphatic stasis is not painful, however lymphedema, due to its volume, may press against vascular-nervous bundles causing mechanical distress. Also, osteo-muscular structures can be stressed by the mere weight of the limb, which in some cases has more than doubled, thus causing widespread pain. As a matter of fact, concurrent homolateral periarthritis humeroscapularis is often present in patients with chronic edema of the upper limb.

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