Typical manifestation of advanced stage chronic lymphedema. The term verrucosis refers to the macroscopic appearance of esophytic lesions, and it has nothing to do with more common dermatologic verrucoid pictures, which, in the majority of cases, are due to viruses (human papilloma virus). Also in lymphostatic verrucosis, skin hyperplasia is present, which, in this case, is caused by increased pressure of interstitial fluid in the derma, promoting the proliferation of epidermal basal layer cells through the compression of their intercellular joints. Lymphostatic verrucosis is often accompanied by lymph leak (lymphorrhea or lymphorrhagia). 

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