Lymphatic valves are identical to venous valves, but they are many more in number. The peculiar rosary-shape of lymphatic vessels is due to the arrangement of these valves, which consist of endothelial cell laminas in seamless connection with the intima of the lymphatic vessel. They lack smooth muscle cells. Just like in the nervous system, lymphatic valves are arranged to follow the flow direction and are located to allow a quick flow of the lymph through the larger lymphatics, while preventing its back-flow.

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