This term refers to inadequate development during the embryonic-fetal period of the anatomical structures responsible for lymph drainage, which are therefore hypoplastic and often insufficient for the normal drainage of lymph. There are different degrees of lymphatic hypoplasia: in the most severe cases, lymphatic insufficiency becomes clinically apparent shortly after birth, while in cases where the deficit is mild, it may become evident clinically after many years, or in conjunction with traumatic or surgical injuries that damage lymphatic structures. In the image: Macroscopic and microscopic pathological alterations involving lymph node structures and lymphatic collectors in peripheral lymphedema due to lymphatic hypoplasia (and hypodysplasia). 

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