It is a liquid, mostly watery in appearance, originating from the interstitial fluid and absorbed by the “initial lymphatics.” It distinguishes itself from other bodily fluids due to its high concentration of proteins and macromolecules. Its function is diverse and, even today, some aspects remain not entirely clear.


It serves a fundamental role in transporting materials, particularly macromolecules, that cannot be otherwise drained by the normal bloodstream. Furthermore, it plays a crucial role in facilitating communication between lymph nodes and peripheral tissues, thus enabling an adequate cell-mediated immune response. For a more comprehensive discussion on its specific physicochemical characteristics, reference to a physiology textbook is recommended. 

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