Laser therapy is a very common therapeutic method in lymphology. It is employed either alone or in combination with the operative microscope. CO2 Laser is the most common device, which is by now routinely employed also in simple out-patient facilities for the treatment of lymphostatic verrucosis, post-surgical lymphorrheas, and phlebostatic ulcers. It is successfully used in the operating room, for its “welding” effect, typical of the laser, in the treatment of acquired and congenital lymph-chylorrheas, lymphoceles, and lymphangiodysplasias.