Neuro-muscular system dysfunction with indirect repercussions on the physiological progression of the lymph from the periphery to the trunk. Lymphatic drainage is significantly reduced by the absence, especially if prolonged, of muscular activity. Therefore, in individuals without a perfectly healthy and functioning lymph-venous system, a lymph-venous edema may develop, called functional “disuse” lymphedema. Patient’s conditions, however, can get better through reactivation of adequate motility or with the use of external muscle stimulators and or compression stockings, which, respectively, stimulate and amplify any contractile action deficit.

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