It is an acute inflammation of superficial soft tissues, most frequently caused by Streptococcus pyogenes. Its clinical picture features an erythematous, stinging edema, with sharply demarcated raised edges, which can involve the face or the extremities, and it is often associated with high fever (up to 41° axillary temperatures). It has highly different systemic pictures, rarely does it affect deeper soft tissues, and it is easily resolved when treated with penicillins. After about 5-10 days since the acute episode, massive exfoliation of the involved skin can occur. Patients affected by lymphedema carry a higher risk of developing this infection. In these individuals, lymphangites, although not necessarily linked to infections by Streptococcus pyogenes, present with mixed clinical pictures that are called “erysipeloid lymphangites”.