Chyle is a milky-white liquid substance described by Gaspare Aselli in 1627. It is drained by the lymphatic vessels starting from the intestinal villi. Chyle differs from peripheral lymph due to the abundant presence of lipoproteins, which, due to their weight and size, cannot penetrate the blood capillaries but only the lymphatic ones. Glycerol, medium and short-chain fatty acids, and steroids are drained into the portal venous circulation. For this reason, many patients with a concurrent chylous component, such as those with “reflux” disorders, are prescribed a diet devoid of complex fats and advised to use MCT Oil, which contains only medium-chain triglycerides that are primarily drained through the portal circulation. 

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