Although words like lymphocyte, lymph node, lymph, and lymphatic vessels are common in daily medical activities, Lymphology has always been considered as a sort of younger sister to Angiology or Phlebology. Also, apart from few pioneer physicians, it has never been investigated as a discreet, well identified area of research.

Therefore, the following “Dictionary” aims to be a sort of metaphorical “window” on the extensive and still poorly explored world of lymphatic diseases, as well as to provide some useful, basic information for a correct diagnosis of patients affected by lymphatic-lymph node disorders.

Questo “Dizionario” vuole, quindi, rappresentare una sorta di metaforica “finestra” sul vasto ed ancora poco inesplorato mondo della patologia linfatica e fornire utili elementi di conoscenza di base per una corretta diagnosi e gestione del paziente affetto da alterazioni del sistema linfatico-linfonoidale.


It is a flavanone, a direct precursor of diosmin (see), prolonging and strengthening its pharmacological activity. Further, it has strong anti-inflammatory effects.


First described by Hennekam in 1988, it is an extremely rare autosomal recessive disorder, characterized by mental retardation associated with gastro-intestinal lymphangectasia, cranial-facial anomalies (hypertelorism, etc.), and lymphedema of the lower limbs and external genitalia. In some cases, also ear and foot anomalies (talipes equinus) have been described. It is one of several syndromes involving the lymphatic system.

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