Dizionario

D

Although words like lymphocyte, lymph node, lymph, and lymphatic vessels are common in daily medical activities, Lymphology has always been considered as a sort of younger sister to Angiology or Phlebology. Also, apart from few pioneer physicians, it has never been investigated as a discreet, well identified area of research.

Therefore, the following “Dictionary” aims to be a sort of metaphorical “window” on the extensive and still poorly explored world of lymphatic diseases, as well as to provide some useful, basic information for a correct diagnosis of patients affected by lymphatic-lymph node disorders.

Questo “Dizionario” vuole, quindi, rappresentare una sorta di metaforica “finestra” sul vasto ed ancora poco inesplorato mondo della patologia linfatica e fornire utili elementi di conoscenza di base per una corretta diagnosi e gestione del paziente affetto da alterazioni del sistema linfatico-linfonoidale.

DYNAMIC LYMPHATIC INSUFFICIENCY

This condition is brought about when the lymphatic load exceeds the total functional capacity of the total lymphatic circulation system.

DIURETICS

Literally, those drugs that can increase diuresis – namely the secreted daily urine volume – are classified as such. Most diuretics act directly on the nephron, through activation of specific transport proteins that are located on the epithelial cell membrane. Their role in lymphatic disorders is limited. They are mostly employed post-operatively – provided the patient’s pressure values allow it – as a mild stimulation to kidney function, and in order to control the daily hydroelectrolytic balance.

DIOSMIN

The most active substance in the gamma-benzopyrone or flavonoid family, on the veins, the lymphatic system, and microcirculation. It is contained in the flavedo of citrus fruits (found in the peel of lemons, oranges, mandarins, and other citrus fruits), or it can also be obtained by partial chemical synthesis.

DEXTRAN

Synthetic polymer of glucose, with a molecular weight of 40,000 or 70,000 daltons. The smallest 40,000 dalton molecules have an “anti-sludge” effect, which promotes microcirculation. For this reason, it is often used in microsurgery to prevent microthrombotic events of anastomoses. Since it may trigger anaphylactic reactions, initially it must be administered slowly, under careful patient monitoring.

DERMAL BACK FLOW

It occurs in severe cases of lymphostasis in which lymphatic back flow is often present in the superficial skin layers up to the derma.

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