They are short-stretch bandages containing a paste of zinc oxide and other active substances (natural coumarins, glycerol, calcium chloride, etc.). They are employed in the treatment of venous disorders – e.g. in postphlebitic syndrome – or in lymphatic disorders, for example in acute and chronic lymphangitis, in particular owing to their anti-inflammatory, antibacterial, exudate-absorbing activity, hence for their trophic effect on tissues involved by irritative-dystrophic processes.



Benzopyrones are a heterogeneous group of chemical substances mostly of plant origin, with a basic structure consisting of a benzenic ring, where an oxygen molecule replaces a carbon one. There are two main classes of benzopyrones: alpha-pyrones (coumarins) and gamma-pyrones (diosmin, hesperidin, rutin).



From a chemical point of view, BPV is a monosodium salt in methanol used in lymphology as a stain for in vivo detection of lymphatic structures. Owing to its chemical composition, it has a remarkable tropism for lymphatics and, when injected into the tissues, it is almost completely drained through all major lymphatic collectors and structures. It is excreted by the kidneys. In some individuals, it may cause allergic reactions.